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8 Topiramate side effects and health risks Topiramate use for weight loss can cause many adverse effects, such as: 1,2 Nervousness Drowsiness Numbness in feet or hands Shaking or tremors Nausea, stomach pain, and constipation Excessive menstrual bleeding Missed menstrual periods Bone pain Weight loss Serious side effects may include: 1,2 Hyperthermia Suicidal ideation Impaired liver function and liver disease Bloody or cloudy urine Painful urination Usual bruising or bleeding Intense side or back pain Fever If you experience any troubling side effects of topiramate or an unusual or allergic reaction, call your doctor immediately

Short-acting agents like exenatide often cause more gastroparesis (slow gastric emptying), while long-acting ones like dulaglutide may be better tolerated

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These cells appear to serve as a crucial transitional population, possibly bridging the gap between undifferentiated stem cells and mature enterocytes