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They can range from mild skin irritation to more serious symptoms

Hauge, C., Breitschaft, A., Hartoft-Nielsen, M

however, adherence to weight-reducing programs or sustaining lifestyle changes is a frustrating challenge for many people (6)

This is the same as taking a double dose and could increase the risk of serious side effects

In children with PWS, those who are heterozygous or homozygous for the d3 allele are more sensitive and responsive to GH treatment, leading to a significant increase in growth compared to those who are homozygous for the full-length GHR allele (136)