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on this structure, all the aminoacidic residues, including high mobility zones, were constructed using a residual electron density with the aim of using these coordinates for MD calculations in apo and holo forms

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In addition, molecular docking results showed that curcumin has affinity for the ligand pocket of the MRGPRX2 protein, indicating that curcumin can inhibit the activation of MRGPRX2 [133]

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