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Generally, if the receptors are ligand-gated ion channels, a conformational change opens the ion channels, which leads to a flow of ions across the cell membrane resulting in either a depolarization, for an excitatory receptor response, or a hyperpolarization, for an inhibitory response [277]

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[DOI] [PubMed] [Google Scholar] 60.Jones K.L., Rigda R.S., Buttfield M.D.M., et al

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