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Peer-reviewed studies explicitly addressing oral health consequences of tongue piercings were eligible, including case reports, observational studies, and reviews

Rosenstock J, Buse JB, Azeem R, Prabhakar P, Kjems L, Huang H, et al

doi: 10.1111/SPOL.12675 220 SaunesISVrangbkKByrkjeflotHJervelundSSBirkHOTynkkynenLKet al

The reality check: the FDA does not consider it a legal cosmetic or dietary ingredient, and there is real concern that long-term use raises the risk of melanoma (skin cancer) the opposite of what most people assume a tan in a vial would do for skin safety (WebMD)

Interestingly, T3 treatment had no effect on the GLP-1 levels in the culture medium of enteroendocrine STC-1 cells, NCI-H716 cells, and mouse intestinal organoids (Supplementary Fig