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Clin Drug Investig 39(8):805819

Are overweight or obese and have not achieved significant weight loss through diet and exercise alone

All claims in this section are supported by peer-reviewed research

Furthermore, the REWIND trial demonstrated a 12% reduction in major adverse cardiovascular events (MACE) ( p = 0.026), including among patients without established cardiovascular disease, alongside renoprotective effects evidenced by reductions in albuminuria [56]

If you can feel satisfied with a smaller amount of food, youll consume fewer calories, which may be one of the best ways to lose weight and keep it off