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Mechanism of Action GLP1 and glucose-dependent insulinotropic polypeptide (GIP, which is combined with GLP1 in dual GLP1/GIP receptor agonists such as tirzepatide) are hormones that increase insulin secretion
investigated the role of 8-hydroxy-2-deoxyguanosine (8-OHdG), an oxidatively modified DNA base and biomarker of oxidative distress [179,633,634,635], and its paradoxical role as exogenous anti-inflammatory and anti-oxidative component [636]
Starting with the lowest possible dose means any initial side effects are likely to be milder and more manageable
They can advise you on the right dosage schedule, address GLP-1 nausea or any other side effects that come up, and help you stay motivated during titration