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Inbreeding can result from the repeated breeding of specific animals to preserve certain desirable characteristics of a particular breed

10.1038/jid.2009.133 44 CostaR.Costa LimaS

[7] Most TRT side effects are dose-dependent and manageable with proper monitoring

Fumarate increases the levels of H 2 O 2 in the renal medulla in vivo and cultured human renal epithelial cells in vitro, the mechanism of which remains unclear 78,82