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MOTS-C MOTS-c (mitochondrial open reading frame of the 12S rRNA-c) is a naturally occurring peptide encoded within mitochondrial DNA, playing a key role in cellular metabolism and energy regulation

+ The characteristic blue colouration comes from the copper(II) ion bound within the tripeptide complex

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If additional glycemic control is needed, the dose can be increased by 2.5 mg every 4 weeks, and the maximum dose of this drug is 15 mg once a week

Emerging research in the gut-brain axis and the protection or disruption by gut microbial-derived metabolites have on BBB integrity are only beginning to be explored