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ODT formulations have not undergone clinical trials and their effectiveness has not been established.

Taking more than the recommended serving does not necessarily mean faster results

Food and Drug Administration (FDA) recommends a maximum daily limit of 4,000 mg of acetaminophen, but individuals in recovery should be advised to take the lowest effective dose

After 12 weeks of follow up, both groups showed a statistically significant reduction in pain measured by VAS, but there was no significant difference between the two treatment arms