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Previous studies have shown that AngIV and its analogs could enhance cognitive ability in rodents and rescue cognitive impairment induced by cerebral ischemia [11,12]

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Furin, as termed as paired basic amino acid cleaving enzyme (PACE), has been found in the fluid from the mid-caput to the distal corpus regions of the epididymis and also in testis of various domestic mammals through immunochemistry and mass spectrometry analyses [19]

However, this risk increases when combined with insulin or sulfonylureas