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Castrejon JL, Berry N, El-Ghaiesh S, Gerber B, Pichler WJ, Park BK, et al

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Doses above 2ml per injection show diminishing returns: a 2019 study published in the Journal of Clinical Endocrinology found no additional improvement in hepatic fat fraction when methionine doses exceeded 50mg per injection, and injection site soreness increased proportionally above this threshold

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