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In addition, the FoxO4/ectonucleotide pyrophosphatase/phosphodiesterase family member 2 axis and the TRIM21/NRF2 axis can inhibit ferroptosis, thereby alleviating doxorubicin-induced cardiotoxicity

This is supported by studies that show that GLP-1 coadministration with somatostatin receptor antagonists eliminates the glucagon-suppressing effects of GLP-1 [30]

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This includes a full counteraction of alcohol intoxication, both acutely and chronically, indicating its active gut-brain axis or brain-gut axis functioning

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