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Levels of glutathione synthetase (GSS) were determined using Human Glutathione Synthetase ELISA Kit (Abcam, Cambridge, UK), while levels of glutathione (GSH) were determined with the GSH+GSSG / GSH Assay Kit (Colorimetric) (Abcam, Cambridge, UK)

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Further studies based on the regulation of xCT expression, ROS stress and redox homeostasis, and energy stress caused by specific nutrient addiction or deficiency will increase the clinical importance of ferroptosis modulation as an effective therapeutic strategy for ovarian cancer

Mitochondrial recycling of ascorbic acid from dehydroascorbic acid: dependence on the electron transport chain

In a study on myocardial IRI in diabetic rats, NAC alleviated ferroptotic cell death and oxidative injury[148]