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Proper documentation and controlled laboratory procedures are required to maintain safety, reproducibility, and experimental integrity

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Ramsay RR, Naismith JH

CLINICAL CONSEQUENCES OF AGE-RELATED DECREASE IN GH SECRETION Aging and GH deficiency both lead to reduced protein synthesis, loss of lean and bone mass, and increased body fat

reviewed 353 cases of OMM and found that the mean age at OMM incidence was 43.1 years with significant female predominance, most often on the lower lip, and more commonly in brown color with a mean size of 6.8 mm (8)