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Ishihara, et al., Tributyltin induces oxidative stress and neuronal injury by inhibiting glutathione S-transferase in rat organotypic hippocampal slice cultures

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Other concerns flagged included suspicions around the timeline between attaining ethical approval and actually commencing the study, the fact that the trial was not randomized considered by many to be the gold standard for clinical trials and the removal of four treated patients from the final dataset, three of whom were escalated to intensive care and one of whom died

The solid was washed with cold diethyl ether/heptane 1/1 v/v (40 mL), dissolved in water and the solution was lyophilized