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These are individual user-reported experiences

The gradual escalation lets the GI tract adapt and dramatically improves tolerability

Lancet Reg Health West Pac 25:100494 Zhang L, Zhang LingYu, Li L et al (2019) Semaglutide is neuroprotective and reduces -synuclein levels in the chronic MPTP mouse model of Parkinsons disease

Sometimes Id eat at 8 or 9 pm, and this would cause acid reflux when I went to bed at 11 pm because Retatrutide slows down stomach emptying, and Id still feel like there was a lot of food in my stomach

In the Phase 2 trial, GI side effects were dose-dependent and generally mild to moderate in severity