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doi:10.2337/diabetes.50.1.96 Granado M, Garca-Cceres C, Frago LM, Argente J, Chowen JA

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For example, the ethanol-inducible CYP2E1, which is located in the centrilobular hepatocytes, effectively catalyzes the centrilobular hepatotoxicity of acetaminophen, carbon tetrachloride, benzene, and nitrosamines