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Augmentation of IGF-I levels in the muscle increases AR clearance through the ubiquitin-proteasome system and AR phosphorylation by Akt[40], and in a mouse model of SBMA, muscle-specific overexpression of IGF-I was able to improve motor performance and body weight [40]

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The effect of glucagon-like peptide-1 receptor agonist therapy on body mass index in adolescents with severe obesity: a randomized, placebo-controlled, clinical trial

Differently from other groups macrophage infiltrations were seen and collagen deposition was increased in this group (Fig

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