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A single morning dose might produce a strong effect for a few hours, but by the next day, the enzyme could be fully active again

As such the overall impact of the manuscript would benefit greatly by detailed editing and potential re-organization. Response: As per your suggestion, we have replaced the section on requirements and detection of dimers with a reference to the original IUPHAR publication

ADT works by interfering with the production of androgens and/or by competing with androgen binding to AR [4]

Because Ozempic is a relatively new medication, there are no generic forms available yet on the market

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