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Zhang J, An H, Ni K, Chen B, Li H, Li Y, et al

AstaReal Astaxanthin helps protect cell membranes from oxidative stress

Single-cell RNA-seq reveals transcriptomic heterogeneity and post-traumatic osteoarthritis-associated early molecular changes in mouse articular chondrocytes

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The study reveals that matrix stiffness modulates H3K27me3 demethylation by the opening of mitochondrial permeability transition pores and the translocation of plant homeodomain finger protein 8, subsequently affecting the expression of Mmp13 and Bax genes, which exacerbates the progression of OA [104]