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The product reached the market at end-2023, and due to several factors (Novo supply constraints, versions available from compounding pharmacies, and the attractive profile) the product is gaining market share and has now captured more than 50% of total volumes in the US

From a patient burden standpoint, people living with advanced CKD take a number of oral medications and may prefer a once-weekly injection to an additional daily oral medication

2021 doi: 10.1172/JCI146353

The open question is whether resistance training and high protein intake (1.62.2g/kg/day) can shift that ratio and early data from athletes suggests it can

doi: 10.1210/clinem/dgac082 2 TauberMHoybyeC