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It's whether the research question justifies the added complexity

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This distinguishes it from better-known compounds such as semaglutide (Ozempic/Wegovy), which targets only the GLP-1 receptor, and from tirzepatide (Mounjaro/Zepbound), which is a dual GLP-1/GIP agonist

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Blood 102(6):20992107 Soro S et al (2008) A proangiogenic peptide derived from vascular endothelial growth factor receptor-1 acts through 51 integrin

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The 4-6 weeks on / 2 weeks off convention is entirely community-derived and not validated in any clinical trial

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