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Do not double the dose to compensate

The risk of developing these severe side effects is very small, but it is important that patients and healthcare professionals are aware and alert to the associated symptoms. An estimated 1.6 million UK adults used GLP-1s such as semaglutide (Wegovy, Ozempic) and tirzepatide (Mounjaro) to lose weight between early 2024 and early 2025, with an additional 3.3 million interested in using weight loss drugs during 2026

Trans stilbenes such as resveratrol have been shown to activate Nrf-2 and exert potent anti-tumour action inhibiting cancer invasion and metastasis [64,65]

DPNs clinical manifestations of DPN typically begin with symmetrical distal limb numbness and sensory loss, progressing to neuropathic pain in approximately 20% of cases

A randomised controlled trial with 961 participants compared the impact of a once-weekly dose of 1 mg or 2 mg of semaglutide on blood glucose levels and weight loss for people living with type 2 diabetes