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Nutrition, particularly adequate protein, micronutrients, and metabolic flexibility, ensures the brain is supplied with the substrates required to meet its exceptionally high energy demands [32]

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Clinical trial data and post-marketing surveillance indicate that gastrointestinal adverse effects are among the most frequent reasons for treatment discontinuation

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These findings are derived from a small number of trials, and the overall ASD sample size remains limited, which restricts the generalizability of the results