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n = 5), and IGF-1 plus L2-Cmu ( n = 5 for lung and n = 6 for heart)

Research protocols sometimes combine matrikine signals with broader gene modulators to address both the targeted collagen induction pathway and the broader tissue remodeling network simultaneously

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Recent studies have also shown that SAM can act as a therapeutic agent for treating depression, as an antidepressant in Parkinsons disease, and in endogenous and bipolar patients with depression and hypomanic symptoms (67)

The study authors note that this effect size is similar to what is observed with many approved drug therapies, minus the side effects and costs