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Experts have become increasingly concerned about nitrous oxide and its potential harms, particularly amid the rise of super-size stainless steel canisters, which came onto the market in around 2017 to "deliberately target" recreational users, according to a recent European Monitoring Centre for Drugs and Drug Addiction report

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LA=long acting Table 3: Effect of Saxagliptin on Systemic Exposures of Coadministered Drugs ND=not determined