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Human bone marrow mesenchymal stem cell-derived extracellular vesicles (hBMSC-EVs) have shown promise in counteracting ROS-induced ALP overactivation ( In vitro and in vivo studies demonstrate that hBMSC-EVs reduce ROS, enhance antioxidant defenses (e.g., SOD1), and restore SIRT1/PGC-1 signaling
Russell, George
Metaflammation: tissue-specific alterations of the NLRP3 inflammasome platform in metabolic syndrome
Differentiation of intestinal stem cells and enteroendocrine cells into L-cells The incretin hormone GLP-1 is one of the hormones that is produced by post-translational processing of proglucagon by proprotein convertase subtilisin-kexin type 1 (Pcsk1) or Pcsk3 in L-cells of the distal small bowel and colon
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