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NAD vs Glutathione: Key Functional Differences Image Source: EMBO Press NAD and glutathione work as two distinct biochemical powerhouses at the molecular level

Factors such as age, body weight, health condition, medication use, and environmental toxin exposure can influence requirements

640 Eicosapentaenoic acid and docosahexaenoic acid can also effectively relieve pentylenetetrazol-induced seizures and depression by reducing iron levels in the brain, promoting M2 polarization of microglia, and activating Nrf2

If improved health and vitality is what you're after, you should also aim to get plenty of B12 through your food, incorporating health-promoting fortified foods like nutritional yeast, natural fortified cereal, and fortified plant milks into your diet (and maybe a few vegan gummy vitamins on top to help with specific issues)