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TFT may normalize TJ expression, macrophage and PTPN2 functions in intestinal epithelial cells, as well as restore epithelial barrier integrity by inhibiting JAK signaling pathway activity [196]

Since skeletal and particularly cardiac muscles depend on fatty acid oxidation for most of their energy, these tissues can be expected to be the most severely affected by carnitine deficiency

PMID: 98 MeldiKMGaconnetGAMayoKE

doi: 10.3390/ijms22157979 148 FogacciFRizzoMKrogagerCKennedyCGeorgesCMGKneeviTet al

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