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[PUBMED Abstract] Eggermont AMM, Blank CU, Mandala M, et al.: Adjuvant Pembrolizumab versus Placebo in Resected Stage III Melanoma

Similar content being viewed by others Introduction Reduced glutathione (GSH) provides the cellular first line of defense against oxidative stress-induced injury, which can be maintained by NADPH generated mainly via the pentose phosphate pathway and its rate-limiting enzyme, glucose-6-phosphate dehydrogenase (G6PD

Karavaeva, D

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It also supports enzymes such as lysyl oxidase, which crosslink collagen fibers and help build a stronger, more stable extracellular matrix [8]