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2000 in Hormone Research showed that 21-day oral AOD-9604 (500 mcg/kg/day) reduced body weight gain by roughly 50% in obese Zucker rats with no insulin sensitivity penalty

If dietary sources arent enough, supplementation can offer a practical solution

Tirzepatide is administered as a once-weekly subcutaneous injection, with a recommended starting dose of 2.5 mg once weekly for 4 weeks, then increasing by 2.5 mg every 4 weeks until the target dose (up to 15 mg) is reached

doi: 10.1136/bjsports-2020-102955 57 OzemekCBonikowskeARChristleJWGalloPM

Neonatal FcR expression in bone marrow-derived cells functions to protect serum IgG from catabolism