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Cold storage never harms probiotics, but heat can kill them, similar to how semaglutide degrades when it gets warm

PMID: 34830978

However, with diabetes, insulin is either absent or does not work properly

Timing: why fasted, and why evening GH secretagogues and GHRH analogs are studied on an empty stomach for a specific reason: dietary fat and the insulin/glucose rise that follows a meal blunt the GH pulse

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