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Contribution of cyp1a2 in the hepatic metabolism of melatonin: Studies with isolated microsomal preparations and liver slices

When NF-kB is overactivated (as it is in chronic inflammatory conditions), it triggers a cascade of pro-inflammatory cytokines including TNF-alpha and IL-6

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Introduction Type 2 diabetes mellitus (T2DM) is a complex, chronic disease that is characterized by insulin resistance and islet -cell dysfunction ( Cholesterol metabolism disorders are an important mechanism in islet dysfunction ( in vivo ( Poly ADP-ribose polymerase (PARP) gene plays a critical role in inducing the damage of diabetic islet cells

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