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There is also growing evidence that neurodegenerative diseases such as Alzheimer's and Parkinson's may be caused by detrimental environmental and dietary factors that alter gene expression by means of DNA methylation and histone modification [3]

In the current HepG2 cell model, in which prolonged exposure is not feasible, the use of relatively high QI concentrations in a short timeframe allows for the identification of underlying mechanisms and pathways, as has been done previously in similar studies with hepatic toxicants (Tafazoli and OBrien, 2009

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These data revealed that Cagri generally had a similar binding mode to amylin peptides but distinct receptor complex dynamics at the calcitonin-family receptors compared to other peptides

Beta-alanine is a non-essential amino acid