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However, this is not a systematic review

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10.1016/0028-3908(94)90039-6 Neuropharmacology 149 MuscoliC.CuzzocreaS.NdengeleM

This ongoing evaluation helps ensure that patients receive optimal benefits while maintaining safety standards throughout their treatment journey

They tested these inhibitors in cell and animal models. They reported changes in intracellular nicotinamide-related metabolites and examined the biological effects of NNMT inhibition under experimental conditions. These outcomes have increased scientific interest in NNMT biology