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Because of this critical connection, it is not surprising that iatrogenic depletion of specific amino acids (i.e., methionine by methioninase 218 , arginine by arginase 219 ) is presently in clinical trials as tumor-selective therapeutic agents, reviewed in ref

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In addition, background references (where appropriate) included menopause, estrogens, women, skin aging, natural products, phytochemicals, polyphenols, and/or combination(s) thereof (without a year-limit range)