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Initiation and progression of PD is dependent upon cellular events, including failures in the protein degradation machinery, oxidative stress, mitochondrial dysfunction, defects in mitochondrial autophagy (mitophagy) and the continuous accumulation of -synuclein, driven through cell to cell interactions between glial cells and neurons that ultimately lead to apoptosis [7,10,18]
N-acetylcysteine (NAC) is a supplement that has been shown to have a variety of health benefits
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Reconstitution is a standard laboratory technique where lyophilised (freeze-dried) powder is dissolved in a suitable solvent to create a liquid solution for analytical testing
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