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Over 26 weeks, heavy drinking days fell by 41.1 percentage points in the semaglutide group versus 26.4 in the placebo group, a 13.7-point treatment difference that reached statistical significance

Quick Answer: Metformin and semaglutide combined produce additive A1C reductions of roughly 1.5 to 2.5% Stacked, you get a broader attack on hyperglycemia: less glucose released from the liver, more insulin secreted in response to meals, less appetite, and slower nutrient absorption

doi: 10.4049/jimmunol.167.12.7094 125 KalafatakisIPatellisACharalampopoulosIGravanisAKaragogeosD

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