Amylin therapies Some drugs currently in development take a different approach, targeting receptors for a different hormone: amylin, which is co-secreted, alongside insulin, by the pancreas to slow gastric emptying, suppress glucagon secretion and signal feelings of fullness
10.1210/jc.2017-00970 54 LevalleyS
Helmstdter J, Keppeler K, Kster L, Mnzel T, Daiber A, Steven S (2022) Glucagon- like peptide-1 (GLP-1) receptor agonists and their cardiovascular benefits-The role of the GLP-1 receptor
Members at or near goal weight optimizing body composition Patients who tolerated standard GLP-1 dosing poorly but want the metabolic benefit Members layering the protocol into a coordinated primary care or mental health strategy Patients with significant weight to lose who would be better served by a standard GLP-1 protocol Personal or family history of medullary thyroid carcinoma or MEN 2 Pregnancy, breastfeeding, or planning pregnancy Expected Timeline What to Expect Microdosing is measured in composition, energy, and how you feel not weekly weigh-ins
doi: 10.1016/j.amjmed.2023.07.016