ozempic vs semaglutide for weight loss GLP-1 vs Wegovy vs Mounjaro Semaglutide vs Ozempic vs Wegovy

Semaglutide works by increasing insulin secretion, decreasing glucagon secretion, slowing gastric emptying, and promoting a feeling of fullness (satiety)

It can indirectly modulate levels of other hormones such as IGF-1 that can potentially affect fertility hormones via common control circuits

Individuals with certain MC4R genotypes may experience a weaker subjective appetite reduction from the same GLP-1 dose not because the medication isn't working pharmacologically, but because the downstream receptor response is genetically attenuated

These drugs work by mimicking the incretin hormone GLP-1, which reduces appetite, slows gastric emptying, and improves appetite suppression signaling in the brain

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