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10.1016/j.ahj.2011.08.004 59

The first is that insulins connection to obesity is complicated, as Ive talked about before in the context of blind, obese, long-lived cavefish3

2 However, the majority of publications presented these results as a secondary outcome in studies targeting the GLP-1 RA effect on patients with diabetes and patients with obesity

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A later ADA conference presentation compared those outcomes to patients who subsequently received GLP-1 agonists and found similar long-term trajectories, though the comparison involved only five patients and wasn't a head-to-head trial [17]