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Description

The added advantage of these combinatorial approaches is that their tumor specificity may abrogate the systemic toxicity associated with single-agent by reducing dose requirements or may enable better therapeutic index in tumors compared to normal tissue

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doi: 10.1007/s00467-018-4005-4 18 HajamYARaniRGanieSYSheikhTAJavaidDQadriSSet al

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Science 336 , 12681273 (2012)

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However, rare but serious side effects may occur

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