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Note that the substantial weight loss from either GLP-1s or bariatric surgery is likely to have higher amounts of cost saving and QALY generation beyond the five years modeled in this study, as many of the complications of obesity are expressed later

Ligand-induced changes in BRET were measured in plasma membrane preparations performed in kinetic mode until kinetic equilibrium was reached for vehicle or increasing concentrations of GLP-1 (left) and TT-OAD2 (right)