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This detrimental progression of liver diseases is often driven by a behavioral cycle involving an increased desire, cravings, and high-calorie food intake during and after alcohol drinking episodes and vice versa

This waiting period helps ensure that the initial dose is both safe and effective before considering an increase

doi: 10.1002/mus.20385 56

Renal (kidney) function : According to the UK SmPC, no dose adjustment is required for patients with renal impairment, including those with severe kidney disease

Data were further filtered by keeping lipids quantified at least in 75% of the analyzed replicates per condition