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Excessive iron promotes the Fenton reaction, generating more ROS, further damaging melanocytes, while glutathione peroxidase 4 (GPX4), a key regulatory factor in ferroptosis, shows significantly downregulated expression in vitiligo

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This long-acting profile is particularly useful in research focused on chronic metabolic regulation and long-term therapeutic potential

BPC-157 was found to be effective in the very low dose range, accelerating wound healing with better granulation tissue formation, re-epithelialisation, dermal remodelling, and higher collagen deposition than the model control group at day 18