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Research published in Biophysical Journal demonstrated that GLP-1 aggregates into low-molecular-weight oligomers that can progress to full fibrillation

A recent meta-analysis of 12 observational studies found that higher dietary intake of vitamin B 12 was associated with a 23% lower risk of depression compared to lower intakes, but stratifying the data revealed a significant protective association in females, not in males (99)

[1] Whilst vitamin B12 deficiency can cause serious health consequences including megaloblastic anaemia and neurological damage, supplementation is generally considered safe

For individuals who are already low in vitamin B12, addressing the deficiency may help support overall energy levels

But it is possible to have negative effects from too much of some of the vitamins if you take supplements