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Ferroptosis: A regulated cell death Nexus linking metabolism, redox biology, and disease

September 5, 2024

GS: Writing review & editing, Writing original draft, Resources

Published Phase 2 data shows: Dose Group Discontinuation Due to AE Placebo 0% 1 mg 2.9% 4 mg (escalated) 5.7% 8 mg (escalated) 5.0% 12 mg (escalated) 8.3% For context, discontinuation rates in semaglutide 2.4 mg trials (STEP program) were approximately 7%, and tirzepatide 15 mg trials (SURMOUNT) reported approximately 6-7%

Growing public concern over chronic disease prevention has led to a surge in demand for early detection tools and health-tech innovations