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Data extraction, management, and conversion Data extraction was independently performed by two authors (PT Tseng and BY Zeng), recording demographic data, study design, treatment details, primary outcomes, and safety information

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Previous meta-analyses have suggested that GLP-1RA/SGLT2i combination therapy can improve blood glucose levels, reduce HbA1c, body weight, and systolic blood pressure compared to monotherapy in T2DM patients [39, 40]