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Theyre marketed as a treatment for type 2 diabetes but both treatments may be prescribed off-label for the long-term management of weight loss

The first was Phentermine-topiramate ER, sold under Qsymia and made by Californian company Vivus, which leads to an 8.5 per cent weight loss after a year of use

the regulatory source for Canadian drug authorization

In an animal study conducted on rodents, Gabery et al

Unlike newer peptides with broader receptor engagement, its single-receptor mechanism allows for some theoretical complementary combinations though the absence of controlled clinical data on combinations with research peptides is a significant caveat that should inform all protocol decisions